Acute Myelogenous Leukemia (AML)

Acute Myeloid Leukemia (AML) is the most common type of acute leukemia affecting adults. Approximately 12,000 cases of acute adult myeloid (myelogenous) leukemia are diagnosed in the United States each year.

Acute Myeloid (Myelogenous) Leukemia: Definition

Acute Myeloid (Myelogenous) Leukemia (AML) is a type of blood cancer in which a type of white blood cells known as “myeloid cells” become cancerous. Healthy myeloid cells are important for killing bacteria. In cases of acute myeloid or myelogenous leukemia, the bone marrow produces abnormal blood cells called “myeloblasts.” This form of leukemia interferes with the normal function of the bone marrow by replacing normal blood cells with leukemia cells. When the abnormal “blast” cells grow out of control, the production of normal blood marrow cells is inhibited, causing a deficiency of red blood cells, normal white blood cells, and platelets. This can lead to such effects as anemia, vulnerability to bruising and bleeding, and increased risk of infection.

Causes of AML

AML is the result of acquired (not inherited) genetic damage to the DNA of developing cells in the bone marrow. Benzene exposure is a known cause of AML. Exposure to certain other toxic solvents, chemicals, and radiation may also be associated with AML.

Subtypes of AML

There are several “subtypes” of AML, including acute myelogenous leukemia, acute myeloid leukemia, acute myelocytic leukemia, acute myeloblastic leukemia, acute granulocytic leukemia (AGL), acute nonlymphocytic leukemia, and acute promyelocytic leukemia (APL).

AML Staging

Unlike many other types of cancer, there is no standard “staging” system for AML. Instead, the disease is described as “untreated,” in “remission,” or “recurrent.”

Symptoms of AML
Diagnosis of AML
Treatment of AML

This Web site is sponsored by the law firm of Baron & Budd, P.C. Please understand that the information provided is not medical advice, but is simply offered as a resource to help you learn about acute myelogenous (myeloid) leukemia (AML) and benzene. Please discuss your health-related questions and concerns with your doctor.

Benzene can cause acute myelogenous leukemia and other blood cancers and disorders. If you have been diagnosed with AML and would like information about your legal rights, please call us at 800-946-9646 or e-mail us at

Please also visit our glossary for helpful definitions of medical terms relating to the diagnosis and treatment of AML.