|
||||||||||||||||||||||||
Chronic Myelogenous Leukemia (CML)Chronic myelogenous leukemia (CML) is a form of leukemia that typically progresses gradually over time as opposed to developing rapidly, as in cases of acute leukemia. Approximately 4,600 cases of CML leukemia are diagnosed in the United States each year. Most cases of chronic myelogenous leukemia occur in adults. Chronic myelogenous leukemia is a type of blood cancer in which the bone marrow produces too many white blood cells, known as “granulocytes.” Some of these cells never mature into white blood cells. These “immature” white blood cells are called “blasts.” Over time, the granulocytes and blasts grow out of control and result in a deficiency of platelets and red blood cells in the bone marrow. This can lead to such symptoms as chronic fatigue, unexplained weight loss, fever and night sweats, and pain or pressure on the left side of the abdomen (where the spleen is located). Unlike acute forms of leukemia, in CML the bone marrow continues to make mature white blood cells that can function normally for quite some time, at least in the early phase of the disease. CML results from an acquired (not inherited) injury to the DNA of a stem cell in the bone marrow. Most people with CML have a gene mutation called the “Philadelphia chromosome.” This chromosome causes the bone marrow to make a certain enzyme, called “tyrosine kinase,” that results in the development of granulocytes or blasts. Benzene exposure can be a cause of CML. Exposure to certain other toxic solvents, chemicals, and radiation may also be associated with CML. There are several “subtypes” of CML, including chronic myelogenous leukemia, chronic myeloid leukemia, chronic myelocytic leukemia, and chronic granulocytic leukemia (CGL).
Symptoms of CML This Web site is sponsored by the law firm of Baron & Budd, P.C. Please understand that the information provided is not medical advice, but is simply offered as a resource to help you learn about chronic myelogenous leukemia (CML) and benzene. Please discuss your health-related questions and concerns with your doctor.
Benzene can cause chronic myelogenous leukemia and other blood cancers and disorders. If you have been diagnosed with CML leukemia and would like information about your legal rights, please call us at 800-946-9646 or e-mail us at Please also visit our glossary for helpful definitions of medical terms relating to the diagnosis and treatment of CML. |
|
|||||||||||||||||||||||
|
||||||||||||||||||||||||
