Having to do with the abdomen, which is the part of the body between the chest and the hips that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
Refers to chronic myelogenous leukemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase but not as high as in the blast phase.
The process of enrolling patients in a clinical research study (trial), or the number of patients already enrolled in a trial or anticipated to enroll in a trial.
A rapidly progressing cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of white blood cells to be produced and enter the blood stream.
ALL. A quickly progressing disease in which too many immature white blood cells (called lymphoblasts) are found in the blood and bone marrow. Also called acute lymphocytic leukemia.
ALL. A quickly progressing disease in which too many immature white blood cells (called lymphoblasts) are found in the blood and bone marrow. Also called acute lymphoblastic leukemia.
AML. A quickly progressing disease in which too many immature white blood cells (not lymphocytes) are found in the blood and bone marrow. Also called acute myeloid leukemia or acute nonlymphocytic leukemia.
AML. A quickly progressing disease in which too many immature white blood cells (not lymphocytes) are found in the blood and bone marrow. Also called acute myelogenous leukemia or acute nonlymphocytic leukemia.
A quickly progressing disease in which too many immature blood-forming cells are found in the blood and bone marrow. Also called acute myeloid leukemia or acute myelogenous leukemia.
Treatment given after the primary treatment to increase the chances of a cure. Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, or biological therapy.
ATLL. An aggressive (rapidly progressing) type of T-cell non-Hodgkin’s lymphoma caused by the human T-cell leukemia virus type 1 (HTLV-1). It is marked by bone and skin lesions, high calcium levels, and enlarged lymph nodes, spleen and liver.
In cancer prevention clinical trials, a study that tests whether taking certain medicines, vitamins, minerals, or food supplements can prevent cancer. Also a called chemoprevention study.
A type of lymphoma that grows and spreads quickly, and has severe symptoms. It is seen frequently in patients who are HIV-positive (AIDS-related lymphoma). Also called intermediate-grade or high-grade lymphoma.
A chemotherapeutic agent such as melphalan or cyclophosphamide. Alkylating refers to the way in which these agents cross-link the DNA of myeloma cells and block cell division.
Acute lymphoblastic leukemia. A quickly progressing disease in which too many immature white blood cells called lymphoblasts are found in the blood and bone marrow. Also called acute lymphocytic leukemia.
A procedure in which a person receives stem cells (cells from which all blood cells develop) from a genetically similar, but not identical, donor. This is often a sister or brother, but could be an unrelated donor.
Practices used instead of standard treatments. They generally are not recognized by the medical community as standard or conventional medical approaches. Alternative medicine includes dietary supplements, megadose vitamins, herbal preparations, special teas, acupuncture, massage therapy, magnet therapy, spiritual healing, and meditation.
Acute myelogenous leukemia. A quickly progressing disease in which too many immature blood-forming cells are found in the blood and bone marrow. Also called acute myeloid leukemia or acute nonlymphocytic leukemia.
A condition in which myeloma light chains (Bence Jones proteins) are deposited in tissues and organs throughout the body. This occurs more commonly with lambda versus kappa Bence Jones proteins. In patients with amyloidosis, the light chain proteins bind to certain tissues such as heart, nerves and kidney rather than being excreted out of the body through the kidneys.
An aggressive (rapidly progressing) type of non-Hodgkin’s lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver.
Drugs or substances that cause loss of feeling or awareness. Local anesthetics cause loss of feeling in a part of the body. General anesthetics put the person to sleep.
A substance that causes loss of feeling or awareness. Local anesthetics cause loss of feeling in a part of the body. General anesthetics put the person to sleep.
An aggressive (rapidly progressing) type of T-cell non-Hodgkin’s lymphoma marked by enlarged lymph nodes and hypergammaglobulinemia (increased antibodies in the blood). Other symptoms may include a skin rash, fever, weight loss, or night sweats.
In medicine, a substance that stops the action or effect of another substance. For example, a drug that blocks the stimulating effect of estrogen on a tumor cell is called an estrogen receptor antagonist.
A type of protein made by plasma cells (a type of white blood cell) in response to an antigen (foreign substance). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Antibodies can work in several ways, depending on the nature of the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen.
Antigen-presenting cell. A cell that shows antigen on its surface to other cells of the immune system. This is an important part of an immune response.
Collection of peripheral blood stem cells by a device similar to a dialysis machine. The blood may be taken from a Hickman or other type of catheter or, if the patient’s veins are good, from the arms. Gathering enough cells for an autologous stem cell transplant may take from one to five days, depending on the amount of stem cells the patient has in their blood.
A type of cell death in which a series of molecular steps in a cell leads to its death. This is the body’s normal way of getting rid of unneeded or abnormal cells. The process of apoptosis may be blocked in cancer cells. Also called programmed cell death.
Adult T-cell leukemia/lymphoma. An aggressive (rapidly progressing) type of T-cell non-Hodgkin’s lymphoma caused by the human T-cell leukemia virus type 1 (HTLV-1). It is marked by bone and skin lesions, high calcium levels, and enlarged lymph nodes, spleen and liver.
In transplantation, refers to a person's own bone marrow. Bone marrow is the soft, sponge-like tissue in the center of most large bones that produces white blood cells, red blood cells, and platelets.
In transplantation, refers to a person’s own white blood cells. Lymphocytes have a number of roles in the immune system, including the production of antibodies and other substances that fight infection and disease.
Stem Cells are taken from the patient’s own body prior to treatment. After treatment, the stem cells are reinfused into the patient to restore the immune system.
For over 27 years, the law firm of Baron & Budd, P.C. has fought to safeguard the rights of victims of toxic substances such as benzene. The Work-Related Leukemia and Lymphoma Medical Web site is a public service of Baron & Budd, P.C.
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