Complementary and alternative medicine. Forms of treatment that are used in addition to (complementary) or instead of (alternative) standard treatments. These practices are not considered standard medical approaches. CAM includes dietary supplements, megadose vitamins, herbal preparations, special teas, massage therapy, magnet therapy, spiritual healing, and meditation.
A monoclonal antibody used to treat leukemia. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. Also called alemtuzumab.
A term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and can spread through the bloodstream and lymphatic system to other parts of the body. There are several main types of cancer. Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the bloodstream. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system.
CIS. The Cancer Information Service is the National Cancer Institute's (NCI) link to the public, interpreting and explaining research findings in a clear, understandable manner and providing personalized answers to questions about cancer. Talk with CIS staff toll-free by calling 1-800-4-CANCER (1-800-422-6237), or reach them online through LiveHelp, NCI's instant messaging service, at http://cancer.gov.
A detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also contain some demographic information about the patient (for example, age, gender, ethnic origin).
A group or series of case reports involving patients who were given similar treatment. Reports of case series usually contain detailed information about the individual patients. This includes demographic information (for example, age, gender, ethnic origin) and information on diagnosis, treatment, response to treatment, and follow-up after treatment.
A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the disease or condition. For example, one group may have been exposed to a particular substance that the other was not. Also called a retrospective study.
A series of detailed pictures of areas inside the body, taken from different angles; the pictures are created by a computer linked to an x-ray machine. Also called computerized axial tomography, computed tomography (CT scan), or computerized tomography.
Complete blood count. A test to check the number of red blood cells, white blood cells, and platelets in a sample of blood. Also called blood cell count.
The process during which young, immature (unspecialized) cells take on individual characteristics and reach their mature (specialized) form and function.
An X-ray of the structures inside the chest. An X-ray is a type of high-energy radiation that can go through the body and onto film, making pictures of areas inside the chest, which can be used to diagnose disease.
A slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow. Also called chronic myelogenous leukemia or chronic myeloid leukemia.
A slowly progressing cancer that starts in blood-forming tissues such as the bone marrow, and causes large numbers of white blood cells to be produced and enter the blood stream.
CLL. A common type of indolent (slowly progressing) cancer in which too many lymphocytes (white blood cells) are found in the peripheral blood and bone marrow. Most patients with CLL are older than 50 years and have no symptoms at the time of their diagnosis.
CML. A slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow. Also called chronic myeloid leukemia or chronic granulocytic leukemia.
CML. A slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow. Also called chronic myelogenous leukemia or chronic granulocytic leukemia.
CMML. A slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone marrow, crowding out other normal blood cells, such as other white blood cells, red blood cells, and platelets.
Refers to the early stages of chronic myelogenous leukemia or chronic lymphocytic leukemia. The number of mature and immature abnormal white blood cells in the bone marrow and blood is higher than normal, but lower than in the accelerated or blast phase.
A phase of chronic myelogenous leukemia that may last from several months to several years. Although there may be no symptoms of leukemia, there are too many white blood cells.
The system that contains the heart and the blood vessels and moves blood throughout the body. This system helps tissues get enough oxygen and nutrients, and it helps them get rid of waste products. The lymph system, which connects with the blood system, is often considered part of the circulatory system.
Cancer Information Service. The CIS is the National Cancer Institute's link to the public, interpreting and explaining research findings in a clear and understandable manner, and providing personalized responses to specific questions about cancer. Access the CIS by calling 1-800-4-CANCER (1-800-422-6237), or by using the Web site at http://cis.nci.nih.gov.
Guidelines developed to help health care professionals and patients make decisions about screening, prevention, or treatment of a specific health condition.
A type of research study that uses volunteers to test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called a clinical trial.
A type of research study that uses volunteers to test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called a clinical study.
Chronic lymphocytic leukemia. A common type of indolent (slowly progressing) cancer in which too many lymphocytes (white blood cells) are found in the peripheral blood and bone marrow. Most patients with CLL are older than 50 years and have no symptoms at the time of their diagnosis.
Chronic myelogenous leukemia. A slowly progressing disease in which too many white blood cells are made in the bone marrow. Also called chronic granulocytic leukemia.
Chronic myelomonocytic leukemia. A slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone marrow, crowding out other normal blood cells, such as other white blood cells, red blood cells, and platelets.
A research study that compares a particular outcome (such as lung cancer) in groups of individuals who are alike in many ways but differ by a certain characteristic (for example, female nurses who smoke compared with those who do not smoke).
A treatment agent used to stimulate the production of certain blood cells in the bone marrow. Agents include granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF).
Care given to improve the quality of life of patients who have a serious or life-threatening disease. The goal of comfort care is to prevent or treat as early as possible the symptoms of the disease, side effects caused by treatment of the disease, and psychological, social, and spiritual problems related to the disease or its treatment. Also called palliative care, supportive care, and symptom management.
A way to provide an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Also called expanded access trial.
CAM. Forms of treatments that are used in addition to (complementary) or instead of (alternative) standard treatments. These practices generally are not considered standard medical approaches. CAM may include dietary supplements, megadose vitamins, herbal preparations, special teas, acupuncture, massage therapy, magnet therapy, spiritual healing, and meditation.
Practices often used to enhance or complement standard treatments. They generally are not recognized by the medical community as standard or conventional medical approaches. Complementary medicine may include dietary supplements, megadose vitamins, herbal preparations, special teas, acupuncture, massage therapy, magnet therapy, spiritual healing, and meditation.
The disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured. Also called a complete response.
The disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured. Also called a complete remission.
CT scan. A series of detailed pictures of areas inside the body taken from different angles; the pictures are created by a computer linked to an x-ray machine. Also called computerized tomography and computerized axial tomography (CAT) scan.
A series of detailed pictures of areas inside the body taken from different angles; the pictures are created by a computer linked to an x-ray machine. Also called CAT scan, computed tomography (CT scan), or computerized tomography.
A series of detailed pictures of areas inside the body taken from different angles; the pictures are created by a computer linked to an x-ray machine. Also called computerized axial tomography (CAT) scan and computed tomography (CT scan).
A clinical study that includes all eligible patients identified by the researchers during the study registration period. The patients are treated in the order in which they are identified. This type of study usually does not have a control group.
A type of high-dose chemotherapy often given as the second phase (after induction therapy) of a cancer treatment regimen for leukemia. Also called intensification therapy.
In a clinical trial, the group that does not receive the new treatment being studied. This group is compared to the group that receives the new treatment, to see if the new treatment works.
A currently accepted and widely used treatment for a certain type of disease, based on the results of past research. Also called conventional treatment.
A group of physicians, hospitals, or both formed to treat a large number of persons in the same way so that a new treatment can be evaluated quickly. Clinical trials of new cancer treatments often require many more people than a single physician or hospital can care for.
A small chemical compound normally excreted by kidney. If the kidneys are damaged, the serum level of creatinine builds up, resulting in an elevated serum cratinine. The serum creatinine test is used to measure kidney function.
Computed tomography scan. A series of detailed pictures of areas inside the body taken from different angles; the pictures are created by a computer linked to an x-ray machine. Also called computerized tomography and computerized axial tomography (CAT) scan.
In medicine, the total amount of a drug or radiation given to a patient over time; for example, the total dose of radiation given in a series of radiation treatments.
A drug used to help reduce the risk of rejection of organ and bone marrow transplants by the body. It is also used in clinical trials to make cancer cells more sensitive to anticancer drugs.
A substance that is produced by cells of the immune system and can affect the immune response. Cytokines can also be produced in the laboratory by recombinant DNA technology and given to people to affect immune responses.
A type of white blood cell that can directly destroy specific cells. T cells can be separated from other blood cells, grown in the laboratory, and then given to a patient to destroy tumor cells. Certain cytokines can also be given to a patient to help form cytotoxic T cells in the patient's body.
For over 27 years, the law firm of Baron & Budd, P.C. has fought to safeguard the rights of victims of toxic substances such as benzene. The Work-Related Leukemia and Lymphoma Medical Web site is a public service of Baron & Budd, P.C.
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